Hi Simon,
That sounds very much like secure unlocking, where a single press on the fob unlocks only the drivers door and a second press unlocks the remainder of doors.
I wonder if you've had your CCCU re-coded recently for anti-hijack, or a repair, and this feathure is now set?
You can verify the single fob press by trying to open the other 3 doors and the tailgate - they should all remain locked if the secure unlocking bits are set in the CCCU
Cheers
Jeff